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RUTAMYCIN
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DeCS
Descriptor
English
:
Rutamycin
Descriptor
Spanish
:
rutamicina
Descriptor
Portuguese
:
Rutamicina
Synonyms
English
:
A 272
A-272
A272
Oligomycin D
RR 32705
RR-32705
RR32705
Tree Number:
D02.540.505.620.750
Definition
English
:
A macrolide antibiotic of the
oligomycin
group, obtained from
Streptomyces
rutgersensis. It is used in
cytochemistry
as a tool to inhibit various ATPases and to uncouple
oxidative phosphorylation
from
electron transport
and also clinically as an antifungal agent.
Pharmacological Action:
Anti-Bacterial Agents
Antifungal Agents
Enzyme Inhibitors
Uncoupling Agents
History Note
English
:
91(75); was see under OLIGOMYCINS 1982-90; was see under ANTIBIOTICS, ANTIFUNGAL 1975-81
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
12800
Unique Identifier:
D012427
Occurrence in VHL
:
Similar:
DeCS