Expresión de búsqueda:
CASPASE 8
Descriptores Encontrados:
1
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1 .. 1
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DeCS
Descriptor
Inglés
:
Caspase 8
Descriptor
Español
:
caspasa 8
Descriptor
Portugués
:
Caspase 8
Sinónimos
Inglés
:
CAP4 Protease
Caspase-8
FLICE Protein
MACH Protein
Mch5 Protease
Pro Caspase 8
Pro-Caspase-8
Procaspase 8
Procaspase-8
Categoría:
D08.811.277.656.262.500.126.550.800
D08.811.277.656.300.200.126.550.800
D12.644.360.024.285.037
D12.644.360.075.405.550.800
D12.644.360.075.421.037
D12.776.157.057.018.037
D12.776.476.024.320.025
D12.776.476.075.405.550.800
D12.776.476.075.421.037
Definición
Inglés
:
A long pro-domain caspase that contains a
death effector domain
in its pro-domain region.
Caspase 8
plays a role in
APOPTOSIS
by cleaving and activating
EFFECTOR CASPASES
. Activation of this enzyme can occur via the interaction of its N-terminal
death effector domain
with
DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS
.
Combinados
Inglés
:
Caspase 8
/
antagonists & inhibitors
use
Caspase Inhibitors
Caspase 8
/
deficiency
use
Alstrom Syndrome
Relacionados
Inglés
:
Autoimmune Lymphoproliferative Syndrome
Nota Histórica
Inglés
:
2007(2000)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52227
Identificador Único:
D053181
Ocurrencia en la BVS
:
Similar:
DeCS