Expresión de búsqueda:
FIBRILLINS
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DeCS
Descriptor
Inglés
:
Fibrillins
Descriptor
Español
:
fibrilinas
Descriptor
Portugués
:
Fibrilinas
Sinónimos
Inglés
:
Fibrillin
Categoría:
D09.400.430.875
D12.776.395.341
D12.776.860.300.400
Definición
Inglés
:
A
family
of
extracellular matrix
glycoproteins
that is structurally
similar
to
LATENT TGF-BETA BINDING PROTEINS
, but contain additional TGF-beta binding domains, in addition to unique domains at their N and C-terminals.
Fibrillins
assemble into 10-12 nm
MICROFIBRILS
that function in a variety of cell interactions with the
EXTRACELLULAR MATRIX
and developmental processes such as
ELASTIC TISSUE
maintenance
and assembly, and the targeting of
growth
factors to the
extracellular matrix.
Nota Histórica
Inglés
:
2017; use FIBRILLIN 1985-2016
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
56519
Identificador Único:
D000071837
Ocurrencia en la BVS
:
Similar:
DeCS