Expresión de búsqueda:
JANUS KINASE 2
Descriptores Encontrados:
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DeCS
Descriptor
Inglés
:
Janus Kinase 2
Descriptor
Español
:
cinasa Janus 2
Descriptor
Portugués
:
Janus Quinase 2
Sinónimos
Inglés
:
JAK 2 Protein Tyrosine Kinase
JAK-2 Protein Tyrosine Kinase
JAK2 Protein Tyrosine Kinase
Categoría:
D08.811.913.696.620.682.725.124.200
D12.776.476.393.200
D12.776.624.664.700.117
Definición
Inglés
:
A Janus kinase subtype that is involved in signaling from
GROWTH HORMONE
RECEPTORS;
PROLACTIN
RECEPTORS; and a variety of CYTOKINE RECEPTORS such as
ERYTHROPOIETIN
RECEPTORS and
INTERLEUKIN
RECEPTORS. Dysregulation of
Janus kinase 2
due to GENETIC TRANSLOCATIONS have been associated with a variety of
MYELOPROLIFERATIVE DISORDERS.
Relacionados
Inglés
:
src Homology Domains
Nota Histórica
Inglés
:
2007(1992)
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
52254
Identificador Único:
D053614
Ocurrencia en la BVS
:
Similar:
DeCS