Expresión de búsqueda: BETA-ARRESTINS 
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Descriptor Inglés:   beta-Arrestins 
Descriptor Español:   beta-arrestinas 
Descriptor Portugués:   beta-Arrestinas 
Sinónimos Inglés:   beta Arrestin
beta Arrestins
beta-Arrestin  
Categoría:   D12.644.360.024.098.525
D12.776.157.057.005.525
D12.776.476.024.104.525
D12.776.543.090.525
Definición Inglés:   Non-visual system arrestins that negatively regulate G-PROTEIN-COUPLED RECEPTORS (GPCRs) and may also function independently of GPCR signaling. They bind and recruit many different signaling factors, including MITOGEN-ACTIVATED PROTEIN KINASES; SRC-FAMILY-KINASES; and FILAMIN to GPCRs and may recognize different phosphorylation states of the receptors to determine the specificity of the cellular response to signaling. 
Nota Histórica Inglés:   2017 (1992) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   56532 
Identificador Único:   D000071557 

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