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DeCS
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Descriptor Inglés:
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Deubiquitinating Enzyme CYLD
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Descriptor Español:
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enzima desubiquitinante CYLD
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Descriptor Portugués:
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Enzima Desubiquitinante CYLD
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Sinónimos Inglés:
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CYLD Protein
CYLD, Deubiquitinating Enzyme
Cylindromatosis Protein
Cylindromatosis, Deubiquitinating Enzyme
Deubiquitinating Enzyme Cylindromatosis
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Categoría:
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D08.811.037.375
D12.776.624.776.482
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Definición Inglés:
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A deubiquitinase and tumor-suppressor protein that specifically cleaves LYSINE-63-linked polyubiquitin chains and also has endodeubiquitinase activity. It functions to regulate NF-KAPPA B and WNT SIGNALING PATHWAY activity, contributing to cell survival, proliferation, and differentiation. Mutations in the CYLD gene are associated with cases of FAMILIAL CYLINDROMATOSIS. |
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Nota Histórica Inglés:
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2018
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Calificadores Permitidos Inglés:
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Número del Registro:
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56989
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Identificador Único:
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D000074749
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Ocurrencia en la BVS:
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Similar:
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DeCS
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