Expresión de búsqueda: MFN=57024 
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Descriptor Inglés:   NADPH Oxidase 2 
Descriptor Español:   NADPH oxidasa 2 
Descriptor Portugués:   NADPH Oxidase 2 
Sinónimos Inglés:   CYBB Protein
Chronic Granulomatous Disease Protein
Cytochrome B 245 Beta Chain
Cytochrome B-245 Beta Chain
GP91 PHOX Protein
GP91-PHOX Protein
NOX2 Protein
Oxidase 2, NADPH  
Categoría:   D08.811.682.608.575.875
D12.776.331.894.875
D12.776.543.653.875
Definición Inglés:   An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE. 
Nota Histórica Inglés:   2018 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   57024 
Identificador Único:   D000074662 

Ocurrencia en la BVS:
 

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