Expresión de búsqueda: MFN=57034 
Descriptores Encontrados: 1
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Descriptor Inglés:   c-Mer Tyrosine Kinase 
Descriptor Español:   tirosina cinasa c-Mer 
Descriptor Portugués:   c-Mer Tirosina Quinase 
Sinónimos Inglés:   Kinase, c-Mer Tyrosine
MERTK
Tyrosine Kinase, c-Mer
c Mer Proto Oncogene Tyrosine Kinase
c Mer Tyrosine Kinase
c-Mer Proto-Oncogene Tyrosine Kinase  
Categoría:   D08.811.913.696.620.682.725.400.003
D12.776.543.750.630.003
D12.776.624.664.700.037
Definición Inglés:   A receptor tyrosine kinase that transduces signals from EXTRACELLULAR MATRIX to the CYTOPLASM by binding ligands such as GALECTIN 3. It regulates many physiologic processes that include cell survival, migration, differentiation, and PHAGOCYTOSIS of apoptotic cells and ROD PHOTORECEPTORS in the RETINAL PIGMENT EPITHELIUM. Mutations in the MERTK gene are associated with type 38 RETINITIS PIGMENTOSA; it also plays a critical role as an inhibitor of TOLL-LIKE RECEPTORS signaling. 
Nota Histórica Inglés:   2018 
Calificadores Permitidos Inglés:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Número del Registro:   57034 
Identificador Único:   D000076202 

Ocurrencia en la BVS:
 

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