Expresión de búsqueda: MFN=57081 
Descriptores Encontrados: 1
Mostrando: 1 .. 1  

 1 / 1 DeCS     
Descriptor Inglés:   Bestrophins 
Descriptor Español:   bestrofinas 
Descriptor Portugués:   Bestrofinas 
Sinónimos Inglés:   BEST 1 Protein
BEST 2 Protein
BEST-1 Protein
BEST-2 Protein
Bestrophin 1
Bestrophin 2
Bestrophin Family
Bestrophin Proteins
Bestrophin-1
Bestrophin-2  
Categoría:   D12.776.157.530.400.175.063
D12.776.306.228
D12.776.543.550.450.175.063
D12.776.543.585.400.175.063
Definición Inglés:   A protein family characterized by a highly conserved N-terminus and four to six transmembrane helices; they function as bicarbonate permeable, calcium-activated chloride channels. Bestrophin-1 (BEST-1) and bestrophin-2 are highly expressed in human RETINAL PIGMENT EPITHELIUM cells and mutations in the BEST-1 gene are associated with VITELLIFORM MACULAR DYSTROPHY, TYPE 2. 
Nota Histórica Inglés:   2018 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   57081 
Identificador Único:   D000075002 

Ocurrencia en la BVS:
 

Similar:

 
DeCS