Expresión de búsqueda: MFN=57096 
Descriptores Encontrados: 1
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Descriptor Inglés:   Centromere Protein A 
Descriptor Español:   proteína A centromérica 
Descriptor Portugués:   Proteína Centromérica A 
Sinónimos Inglés:   Autoantigens 17K, Centromere
CENP A Protein
CENP-A Protein
CENPA Protein
Centromere Autoantigens 17K
Centromere Protein 17K  
Categoría:   D12.776.157.687.173
D12.776.260.123
D12.776.660.235.100
D12.776.660.720.173
D12.776.664.235.100
D23.050.422.031
Definición Inglés:   A 17 kDa, centromeric, poly(ADP)-ribose binding protein that is structurally similar to HISTONE H3 and localizes to NUCLEOSOMES within the CENTROMERE; specifically within the region that binds KINETOCHORES, where it replaces histone H3. It plays a critical role in recruiting kinetochore proteins and progression through MITOSIS, chromosome segregation, and CYTOKINESIS. It also binds sera from patients with some scleroderma-like AUTOIMMUNE DISEASES. 
Nota Histórica Inglés:   2018 (1987) 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   57096 
Identificador Único:   D000076247 

Ocurrencia en la BVS:
 

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DeCS