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DeCS
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Descriptor Inglés:
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Thyroid Nuclear Factor 1
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Descriptor Español:
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factor nuclear tiroideo 1
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Descriptor Portugués:
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Fator Nuclear 1 de Tireoide
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Sinónimos Inglés:
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Enhancer-Binding Protein, Thyroid-Specific
Homeobox Protein Nkx 2.1
Homeobox Protein Nkx-2.1
NK2 Homeobox 1 Protein
Nkx-2.1, Homeobox Protein
TITF 1 Protein
TITF-1 Protein
TITF1 Protein
TTF 1 Thyroid Nuclear Factor
TTF-1 Thyroid Nuclear Factor
Thyroid Specific Enhancer Binding Protein
Thyroid Transcription Factor 1
Thyroid-Specific Enhancer-Binding Protein
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Categoría:
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D12.776.260.400.871
D12.776.660.823
D12.776.930.888
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Definición Inglés:
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A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. It is critical for maintaining thyroid tissue in a differentiated state and also plays a role in lung development. Mutations in the NKX2-1 gene are associated with CHOREA, BENIGN HEREDITARY. |
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Nota Histórica Inglés:
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2018 (1990)
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Calificadores Permitidos Inglés:
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Número del Registro:
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57112
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Identificador Único:
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D000074482
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Ocurrencia en la BVS:
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Similar:
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DeCS
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