Search on: BUTYROPHILINS 
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Descriptor English:   Butyrophilins 
Descriptor Spanish:   butirofilinas 
Descriptor Portuguese:   Butirofilinas 
Synonyms English:   Butyrophilin  
Tree Number:   D12.776.395.550.114
D12.776.543.550.195
Definition English:   A family of mammalian membrane glycoproteins characterized by extracellular IMMUNOGLOBULIN DOMAINS. Some members also have an intracellular B30.2-SPRY DOMAIN or SPRY DOMAIN. The butyrophilin protein (BTN) is expressed by MAMMARY GLAND EPITHELIUM during LACTATION; whereas other members are widely expressed in other tissues, including skeletal muscle, intestine, ERYTHROID CELLS (ERMAP protein); and nerve tissue (MYELIN-OLIGODENDROCYTE GLYCOPROTEIN). 
History Note English:   2017 (1981) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56620 
Unique Identifier:   D000071797 

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