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CHLORMETHIAZOLE
Descriptors Found:
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DeCS
Descriptor
English
:
Chlormethiazole
Descriptor
Spanish
:
clormetiazol
Descriptor
Portuguese
:
Clormetiazol
Synonyms
English
:
Clomethiazole
Distraneurin
Tree Number:
D02.886.675.180
D03.383.129.708.180
Definition
English
:
A sedative and anticonvulsant often used in the treatment of alcohol withdrawal.
Chlormethiazole
has also been proposed as a neuroprotective agent. The mechanism of its therapeutic activity is not entirely clear, but it does potentiate
GAMMA-AMINOBUTYRIC ACID
receptors response and it may also
affect
glycine
receptors.
Pharmacological Action:
Anticonvulsants
Hypnotics and Sedatives
Neuroprotective Agents
GABA Modulators
History Note
English
:
68; CHLORETHIAZOLE was see CHLORMETHAZOLE 1975-95
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
2764
Unique Identifier:
D002719
Occurrence in VHL
:
Similar:
DeCS