Search on: CHLOROQUINOLINOLS 
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Descriptor English:   Chloroquinolinols 
Descriptor Spanish:   cloroquinolinoles 
Descriptor Portuguese:   Cloroquinolinóis 
Tree Number:   D03.633.100.810.350.625.250
Definition English:   8-Hydroxyquinolinols chlorinated on the number 5 and/or 7 carbon atom(s). They are antibacterial, antiprotozoal, and antidiarrheal, especially in amebiasis, and have also been used as antiseborrheics. The compounds are mostly used topically, but have been used also as animal feed additives. They may cause optic and other neuropathies and are most frequently administered in combination with other agents. 
Pharmacological Action:   Amebicides
 
History Note English:   91(65); was see under HYDROXYQUINOLINES 1965-90 (Prov 1965-74) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   2790 
Unique Identifier:   D002739 

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