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DeCS
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Descriptor English:
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Cocaine
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Descriptor Spanish:
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cocaína
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Descriptor Portuguese:
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Cocaína
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Synonyms English:
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Cocaine HCl
Cocaine Hydrochloride
HCl, Cocaine
Hydrochloride, Cocaine
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Tree Number:
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D02.145.074.722.388
D03.132.889.354
D03.605.084.500.722.388
D03.605.869.388
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Definition English:
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An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake. |
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Indexing Annotation English:
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cocaine derivatives = COCAINE /analogs; CRACK COCAINE, COCAINE SMOKING and COCAINE-RELATED DISORDERS are available
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Pharmacological Action:
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Anesthetics, Local
Vasoconstrictor Agents
Dopamine Uptake Inhibitors
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See Related English:
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Cocainum Hydrochloricum
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History Note English:
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COCAINE DERIVATIVES was see under COCAINE 1975-77; was see under TROPANES 1969-74
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Allowable Qualifiers English:
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Record Number:
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3070
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Unique Identifier:
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D003042
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Occurrence in VHL:
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Similar:
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DeCS
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