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COLISTIN
Descriptors Found:
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DeCS
Descriptor
English
:
Colistin
Descriptor
Spanish
:
colistina
Descriptor
Portuguese
:
Colistina
Synonyms
English
:
Colimycin
Colisticin
Colistin Sulfate
Coly-Mycin
Polymyxin E
Sulfate, Colistin
Totazina
Tree Number:
D04.345.566.780.110
D10.477.750.110
D12.644.050.600.110
D12.644.641.780.110
D12.776.543.695.054.600.110
Definition
English
:
Cyclic polypeptide antibiotic from
Bacillus
colistinus. It is composed of
Polymyxins
E1 and E2 (or Colistins A, B, and C) which act as
detergents
on cell
membranes
.
Colistin
is less toxic than
Polymyxin B
, but otherwise
similar
; the methanesulfonate is used orally.
Pharmacological Action:
Anti-Bacterial Agents
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
3122
Unique Identifier:
D003091
Occurrence in VHL
:
Similar:
DeCS