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CYCLOSPORINS
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DeCS
Descriptor
English
:
Cyclosporins
Descriptor
Spanish
:
ciclosporinas
Descriptor
Portuguese
:
Ciclosporinas
Synonyms
English
:
Cyclosporines
Tree Number:
D04.345.566.235
D12.644.641.235
Definition
English
:
A group of closely related cyclic undecapeptides from the fungi
Trichoderma
polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects.
Cyclosporins
have been proposed as adjuvants in
tissue
and
organ transplantation
to suppress
graft rejection.
Indexing Annotation
English
:
do not confuse with
CYCLOSPORINE
, a specific drug
Pharmacological Action:
Enzyme Inhibitors
Immunosuppressive Agents
History Note
English
:
82
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
3544
Unique Identifier:
D003524
Occurrence in VHL
:
Similar:
DeCS