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DENOSUMAB
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DeCS
Descriptor
English
:
Denosumab
Descriptor
Spanish
:
denosumab
Descriptor
Portuguese
:
Denosumab
Synonyms
English
:
AMG 162
Prolia
Xgeva
Tree Number:
D12.776.124.486.485.114.224.060.782
D12.776.124.790.651.114.224.060.782
D12.776.377.715.548.114.224.200.782
Definition
English
:
A humanized monoclonal antibody and an inhibitor of the
RANK LIGAND
, which regulates OSTEOCLAST differentiation and
bone remodeling
. It is used as a
BONE DENSITY
CONSERVATION AGENT in the treatment of
OSTEOPOROSIS.
Pharmacological Action:
Bone Density Conservation Agents
See Related
English
:
RANK Ligand
History Note
English
:
2016 (2004)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55976
Unique Identifier:
D000069448
Occurrence in VHL
:
Similar:
DeCS