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DeCS
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Descriptor English:
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Endoglin
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Descriptor Spanish:
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endoglina
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Descriptor Portuguese:
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Endoglina
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Synonyms English:
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Antigen, CD105
CD105 Antigen
Endoglin Protein
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Tree Number:
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D12.776.543.750.250
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Definition English:
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A membrane glycoprotein and ANGIOGENESIS FACTOR that is expressed by cells of the VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; and MONOCYTES. It functions as a co-receptor for TRANSFORMING GROWTH FACTOR BETA and modulates CELL ADHESION. Mutations in the endoglin gene are associated with cases of HEREDITARY HEMORRHAGIC TELANGIECTASIA. |
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History Note English:
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2017
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Allowable Qualifiers English:
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Record Number:
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56643
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Unique Identifier:
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D000071063
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Occurrence in VHL:
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Similar:
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DeCS
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