Search on:
EPOTHILONE
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Epothilones
Descriptor
Spanish
:
epotilonas
Descriptor
Portuguese
:
Epotilonas
Synonyms
English
:
Epothilon
Epothilone
Tree Number:
D02.540.576.500.984
Definition
English
:
A group of 16-member
MACROLIDES
which stabilize
MICROTUBULES
in a manner
similar
to
PACLITAXEL
. They were originally found in the myxobacterium Sorangium cellulosum, now renamed to Polyangium (
MYXOCOCCALES
).
Pharmacological Action:
Tubulin Modulators
History Note
English
:
2003
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
37309
Unique Identifier:
D034261
Occurrence in VHL
:
Similar:
DeCS