Search on: EPTIFIBATIDE 
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Descriptor English:   Eptifibatide 
Descriptor Spanish:   eptifibatida 
Descriptor Portuguese:   Eptifibatida 
Synonyms English:   Epifibatide
Epifibratide
Integrelin
Integrilin  
Tree Number:   D12.644.641.366
Definition English:   Cyclic peptide that acts as a platelet glycoprotein IIB-IIIA antagonist, reversibly inhibiting the binding of FIBRINOGEN; VON WILLEBRAND FACTOR; and other adhesive molecules to the GPIIB-IIA RECEPTORS of platelets. It is used in the management of UNSTABLE ANGINA and in patients undergoing coronary ANGIOPLASTY and stenting procedures. 
Pharmacological Action:   Platelet Aggregation Inhibitors
 
History Note English:   2019 (1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   57667 
Unique Identifier:   D000077542 

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