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GDF-15
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DeCS
Descriptor
English
:
Growth Differentiation Factor 15
Descriptor
Spanish
:
factor 15 de diferenciación del crecimiento
Descriptor
Portuguese
:
Fator 15 de Diferenciação de Crescimento
Synonyms
English
:
Differentiation Factor, Prostate
GDF-15
Macrophage Inhibitory Cytokine 1
Prostate Differentiation Factor
Tree Number:
D12.644.276.374.305
D12.644.276.954.300.915
D12.776.467.374.305
D12.776.467.942.300.915
D23.529.374.305
D23.529.942.300.915
Definition
English
:
A
growth
differentiation factor that is secreted in response to cell stress and in response to
MACROPHAGE ACTIVATION
. In addition
growth differentiation factor 15
demonstrates a diverse array of biological properties including the induction of
cartilage
formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
History Note
English
:
2009(1997)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
53127
Unique Identifier:
D055436
Occurrence in VHL
:
Similar:
DeCS