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LORATADINE
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DeCS
Descriptor
English
:
Loratadine
Descriptor
Spanish
:
loratadina
Descriptor
Portuguese
:
Loratadina
Synonyms
English
:
4-(8-Chloro-5,6-dihydro-11H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester
Alavert
Claritin
Clarium
Sch 29851
Sch-29851
Sch29851
Tree Number:
D02.455.426.559.847.181.384.340.500
D03.383.621.160.500
D04.615.181.384.340.500
Definition
English
:
A second-generation
histamine
H1 receptor antagonist used in the treatment of allergic
rhinitis
and
urticaria
. Unlike most classical antihistamines (
HISTAMINE H1 ANTAGONISTS
) it lacks
central nervous system
depressing effects such as drowsiness.
Pharmacological Action:
Antipruritics
Anti-Allergic Agents
Histamine H1 Antagonists, Non-Sedating
History Note
English
:
93; was LORATADINE (NM) 1984-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
30666
Unique Identifier:
D017336
Occurrence in VHL
:
Similar:
DeCS