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MILRINONE
Descriptors Found:
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DeCS
Descriptor
English
:
Milrinone
Descriptor
Spanish
:
milrinona
Descriptor
Portuguese
:
Milrinona
Synonyms
English
:
Corotrop
Corotrope
Lactate, Milrinone
Milrinone Lactate
Primacor
Win 47203
Win-47203
Win47203
Tree Number:
D02.092.080.085.543
D03.383.725.050.085.543
Definition
English
:
A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase type 3 activity in
myocardium
and vascular smooth muscle.
Milrinone
is a derivative of
amrinone
and has 20-30 times the inotropic
potency
of
amrinone.
Pharmacological Action:
Cardiotonic Agents
Platelet Aggregation Inhibitors
Vasodilator Agents
Phosphodiesterase 3 Inhibitors
History Note
English
:
99; use MILRINONE (NM) 1983-98
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
33788
Unique Identifier:
D020105
Occurrence in VHL
:
Similar:
DeCS