1 / 1
|
DeCS
|
|
|
Descriptor English:
|
|
Lapatinib
|
Descriptor Spanish:
|
|
lapatinib
|
Descriptor Portuguese:
|
|
Lapatinib
|
Synonyms English:
|
|
GW 282974X
GW 572016
GW-282974X
GW-572016
GW282974X
GW572016
Lapatinib Ditosylate
N-(3-chloro-4-(((3-fluorobenzyl)oxy)phenyl)-6-(5-(((2-methylsulfonyl)ethyl)amino)methyl) -2-furyl)-4-quinazolinamine
Tykerb
|
Tree Number:
|
|
D03.633.100.786.516
|
Definition English:
|
|
A quinazoline derivative that inhibits EPIDERMAL GROWTH FACTOR RECEPTOR and HER2 (RECEPTOR, ERBB-2) tyrosine kinases. It is used for the treatment of advanced or metastatic breast cancer, where tumors overexpress HER2. |
Pharmacological Action:
|
|
Antineoplastic Agents
Protein Kinase Inhibitors
|
History Note English:
|
|
2019 (2004)
|
Allowable Qualifiers English:
|
|
|
Record Number:
|
|
57625
|
Unique Identifier:
|
|
D000077341
|
Occurrence in VHL:
|
|
|
Similar:
|
|
DeCS
|