Search on: MFN=51076 
Descriptors Found: 1
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Descriptor English:   B7-2 Antigen 
Descriptor Spanish:   antígeno B7-2 
Descriptor Portuguese:   Antígeno B7-2 
Synonyms English:   Antigen, B7 2
Antigen, B7-2
Antigen, CD86
Antigens, CD86
B7 2 Antigen
B7-2 Costimulatory Molecule
B70 Costimulatory Molecule
CD86 Antigen
CD86 Antigens
Costimulatory Molecule, B7-2
Costimulatory Molecule, B70
Early T Cell Costimulatory Molecule 1  
Tree Number:   D12.776.467.150.200
D12.776.543.095.200
D23.050.301.285.200
D23.529.168.200
Definition English:   A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE. 
See Related English:   Immunoglobulin Domains
 
History Note English:   2018 (1993) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51076 
Unique Identifier:   D051940 

Occurrence in VHL: 		 

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DeCS