Search on: MFN=56938 
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Descriptor English:   Immunoglobulin Light-chain Amyloidosis 
Descriptor Spanish:   amiloidosis de cadenas ligeras de las inmunoglobulinas 
Descriptor Portuguese:   Amiloidose de Cadeia Leve de Imunoglobulina 
Synonyms English:   AL Amyloidoses
AL Amyloidosis
Amyloidoses, Primary
Amyloidoses, Primary Systemic
Amyloidosis, Immunoglobulin Light chain
Amyloidosis, Immunoglobulin Light-chain
Amyloidosis, Primary
Amyloidosis, Primary Systemic
Immunoglobulin Light chain Amyloidosis
Immunoglobulin Light-chain Amyloidoses
Primary Amyloidoses
Primary Amyloidosis
Primary Systemic Amyloidoses
Primary Systemic Amyloidosis
Systemic Amyloidoses, Primary
Systemic Amyloidosis, Primary  
Tree Number:   C04.557.595.250
C18.452.845.500.550
C20.683.515.507
C20.683.780.565
Definition English:   A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies. 
History Note English:   2018(2010) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   56938 
Unique Identifier:   D000075363 

Occurrence in VHL: 		 

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