DeCS Server - List Exact Term

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DeCS

Descriptor English:

Mechanistic Target of Rapamycin Complex 1

Descriptor Spanish:

diana mecanicista del complejo 1 de la rapamicina

Descriptor Portuguese:

Alvo Mecanístico do Complexo 1 de Rapamicina

Synonyms English:

Complex, mTORC1
TOR Complex 1
TORC1
Target of Rapamycin Complex 1
mTORC1
mTORC1 Complex

Tree Number:

Definition English:

An evolutionarily conserved multiprotein complex that functions as a cellular energy sensor and regulator of protein synthesis for cell growth and proliferation. It consists of TOR SERINE-THREONINE KINASES; REGULATORY-ASSOCIATED PROTEIN OF MTOR (RAPTOR); MLST8 PROTEIN; and AKT1 substrate 1 protein. The activity of the complex is regulated by SIROLIMUS; INSULIN; GROWTH FACTORS; PHOSPHATIDIC ACIDS; some amino acids or amino acid derivatives, and OXIDATIVE STRESS.

History Note English:

2018 (2013)

Allowable Qualifiers English:

Record Number:

56982

Unique Identifier:

D000076222

Similar:

DeCS