Search on: MFN=56983 
Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   MTOR Associated Protein, LST8 Homolog 
Descriptor Spanish:   proteína asociada a MTOR, homóloga de LST8 
Descriptor Portuguese:   Homólogo LST8 da Proteína Associada a MTOR 
Synonyms English:   G protein beta Subunit like Polypeptide
G protein beta Subunit-like Polypeptide
GBetaL Protein
mLST8 Protein  
Tree Number:   D05.500.337.250
D08.811.913.696.620.682.700.931.500.250
D12.644.360.024.310
D12.776.157.057.073
D12.776.476.024.389
D12.776.476.925.500.250
Definition English:   An adaptor protein, consisting of seven WD REPEATS along its length, that functions as a component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 and MTORC2 COMPLEX. It interacts directly with MTOR to enhance its kinase activity and stabilizes the MTOR-RPTOR PROTEIN interaction in nutrient-poor conditions, favoring RPTOR inhibition of MTOR activity. 
History Note English:   2018 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56983 
Unique Identifier:   D000076242 

Occurrence in VHL:
 

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