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MFN=56991
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DeCS
Descriptor
English
:
MutS Proteins
Descriptor
Spanish
:
proteínas MutS
Descriptor
Portuguese
:
Proteínas MutS
Synonyms
English
:
Homolog Proteins, MutS
MutS Homolog Proteins
MutS Homologs
Proteins, MutS Homolog
Tree Number:
D08.811.074.844
D08.811.277.040.025.292
D12.776.260.556
Definition
English
:
DNA repair
proteins
that include the bacterial
MutS DNA mismatch-binding protein
and its eukaryotic homologs that function in
DNA MISMATCH REPAIR
and recombination of DNA during
MEIOSIS
. MutS has a conserved mismatch recognition domain characterized by GxFxE, or
similar
AMINO ACID MOTIFS
that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All
MutS proteins
also contain a highly-conserved ATP-binding domain and most have weak ATPase activity.
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56991
Unique Identifier:
D000074080
Occurrence in VHL
:
Similar:
DeCS