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MFN=57001
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DeCS
Descriptor
English
:
rhoC GTP-Binding Protein
Descriptor
Spanish
:
proteína rhoC de unión a GTP
Descriptor
Portuguese
:
Proteína de Ligação a GTP rhoC
Synonyms
English
:
GTP-Binding Protein, rhoC
ras Homolog Family Member C
rhoC GTP Binding Protein
rhoC GTPase
Tree Number:
D08.811.277.040.330.300.400.700.650
D12.644.360.525.700.650
D12.776.157.325.515.700.650
D12.776.476.525.700.650
Definition
English
:
A rho GTP-binding protein that is prenylated (see
PROTEIN PRENYLATION
) at its C-terminus and cycles between the
cytoplasm
and
plasma
membrane, linking receptor signaling pathways with assembly of
FOCAL ADHESIONS
;
STRESS FIBERS
; and contractile ring formation during
CYTOKINESIS
. It is overexpressed in proliferating and metastatic tumor cells.
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57001
Unique Identifier:
D000075024
Occurrence in VHL
:
Similar:
DeCS