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DeCS
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Descriptor English:
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Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
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Descriptor Spanish:
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proteína 1 de la translocación del linfoma del tejido linfático asociado a mucosas
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Descriptor Portuguese:
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Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa
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Synonyms English:
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MALT 1 Protein
MALT-1 Protein
MALT1 Paracaspase
MALT1 Protein
Mucosa Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
Paracaspase
Paracaspase, MALT1
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Tree Number:
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D08.811.277.656.262.500.126.775
D08.811.277.656.300.200.126.775
D08.811.464.938.750.233
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Definition English:
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A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES. |
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History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57006
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Unique Identifier:
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D000074884
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Occurrence in VHL:
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Similar:
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DeCS
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