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DeCS
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Descriptor English:
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Baculoviral IAP Repeat-Containing 3 Protein
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Descriptor Spanish:
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proteína 3 que contiene repeticiones IAP de baculovirus
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Descriptor Portuguese:
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Proteína 3 com Repetições IAP de Baculovírus
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Synonyms English:
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Apoptosis Inhibitor 2
Apoptosis-2 Cellular Inhibitor
BIRC3 Protein
Baculoviral IAP Repeat Containing 3 Protein
Baculoviral IAP Repeat Containing Protein 3
Cellular Inhibitor of Apoptosis 2
Cellular Inhibitor of Apoptosis-2
Hiap 1 Protein
Hiap-1 Protein
IAP1 Protein
Inhibitor 2, Apoptosis
Inhibitor of Apoptosis 1 Protein
Inhibitor of Apoptosis Protein 1
c-IAP2 Protein
cIAP2 Protein
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Tree Number:
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D08.811.464.938.750.210.250
D12.644.360.075.437.250
D12.776.476.075.437.250
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Definition English:
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A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells. |
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Pharmacological Action:
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Caspase Inhibitors
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History Note English:
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2018; for INHIBITOR OF APOPTOSIS 1 PROTEIN use INHIBITOR OF OF APOPTOSIS PROTEINS 2006-2017
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Allowable Qualifiers English:
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Record Number:
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57011
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Unique Identifier:
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D000075747
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Occurrence in VHL:
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Similar:
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DeCS
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