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DeCS
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Descriptor English:
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NADPH Oxidase 2
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Descriptor Spanish:
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NADPH oxidasa 2
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Descriptor Portuguese:
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NADPH Oxidase 2
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Synonyms English:
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CYBB Protein
Chronic Granulomatous Disease Protein
Cytochrome B 245 Beta Chain
Cytochrome B-245 Beta Chain
GP91 PHOX Protein
GP91-PHOX Protein
NOX2 Protein
Oxidase 2, NADPH
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Tree Number:
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D08.811.682.608.575.875
D12.776.331.894.875
D12.776.543.653.875
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Definition English:
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An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE. |
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History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57024
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Unique Identifier:
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D000074662
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Occurrence in VHL:
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Similar:
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DeCS
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