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DeCS
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Descriptor English:
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Positive Regulatory Domain I-Binding Factor 1
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Descriptor Spanish:
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factor 1 de unión al dominio 1 de regulación positiva
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Descriptor Portuguese:
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Fator 1 de Ligação ao Domínio I Regulador Positivo
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Synonyms English:
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B Lymphocyte Induced Maturation Protein 1
B Lymphocyte-Induced Maturation Protein 1
BLIMP1 Protein
PRDI BF1 Protein
PRDI-BF1 Protein
PRDM1 Protein
Positive Regulatory Domain I Binding Factor 1
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Tree Number:
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D08.811.913.555.500.800.700
D12.776.260.703.650
D12.776.930.780.904
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Definition English:
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A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs. |
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See Related English:
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PR-SET Domains
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History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57030
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Unique Identifier:
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D000074462
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Occurrence in VHL:
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Similar:
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DeCS
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