Search on: MFN=57036 
Descriptors Found: 1
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Descriptor English:   Disks Large Homolog 4 Protein 
Descriptor Spanish:   homólogo 4 de la proteína discs large 
Descriptor Portuguese:   Proteína 4 Homóloga a Disks-Large 
Synonyms English:   Discs Large Homolog 4 Protein
PSD 95 Protein
PSD-95 Protein
PSD95 Protein
Postsynaptic Density Protein 95
SAP 90 Protein
SAP-90 Protein
SAP90 Protein
Synapse Associated Protein 90
Synapse-Associated Protein 90  
Tree Number:   D08.811.913.696.650.450.750
D12.644.360.265
D12.776.476.265
D12.776.543.219
D12.776.631.224
Definition English:   A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY. 
See Related English:   SAP90-PSD95 Associated Proteins
 
History Note English:   2018 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   57036 
Unique Identifier:   D000076122 

Occurrence in VHL:
 

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DeCS