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DeCS
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Descriptor English:
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Angiopoietin-like 4 Protein
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Descriptor Spanish:
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proteína 4 similar a la angiopoyetina
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Descriptor Portuguese:
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Proteína 4 Semelhante a Angiopoietina
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Synonyms English:
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ANGPTL4 Protein
Angiopoietin like 4 Protein
Angiopoietin like Protein 4
Angiopoietin related Protein 4
Angiopoietin-like Protein 4
Angiopoietin-related Protein 4
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Tree Number:
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D12.644.276.100.050.500
D12.776.467.100.050.500
D23.529.100.050.500
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Definition English:
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A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis. |
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History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57048
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Unique Identifier:
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D000075803
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Occurrence in VHL:
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Similar:
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DeCS
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