Search on: MFN=57059 
Descriptors Found: 1
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Descriptor English:   Inhibitor of Growth Protein 1 
Descriptor Spanish:   proteína inhibidora del crecimiento 1 
Descriptor Portuguese:   Proteína 1 Inibidora do Crescimento 
Synonyms English:   ING 1 Protein
ING-1 Protein
ING1 Protein
p33ING Protein  
Tree Number:   D12.644.360.368
D12.776.476.383
D12.776.624.776.503
D12.776.660.494
Definition English:   A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS. 
History Note English:   2018 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   57059 
Unique Identifier:   D000076023 

Occurrence in VHL:
 

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