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DeCS
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Descriptor English:
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Serine Peptidase Inhibitor Kazal-Type 5
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Descriptor Spanish:
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inhibidor de serinpeptidasas tipo Kazal-5
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Descriptor Portuguese:
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Inibidor de Serinopeptidase do Tipo Kazal 5
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Synonyms English:
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Inhibitor, Lympho-Epithelial Kazal-Type
Kazal-Type Inhibitor, Lympho-Epithelial
LEKTI Protein
Lympho Epithelial Kazal Type Inhibitor
Lympho-Epithelial Kazal-Type Inhibitor
SPINK5 Protein
Serine Peptidase Inhibitor Kazal Type 5
Serine Protease Inhibitor Kazal Type 5
Serine Protease Inhibitor Kazal-Type 5
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Tree Number:
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D12.644.822.750.250
D12.776.645.688.250
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Definition English:
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A secreted serine peptidase inhibitor that consists of 15 KAZAL MOTIFS and inhibits KALLIKREINS KLK5, KLK7, and KLK14 as well as TRYPSIN. It plays important roles in protecting MUCOSA against infection and inflammation, and in maintaining the integrity of the skin. Mutations in the SPINK5 gene are associated with NETHERTON SYNDROME. |
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See Related English:
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Kazal Motifs
Netherton Syndrome
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History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57063
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Unique Identifier:
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D000074163
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Occurrence in VHL:
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Similar:
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DeCS
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