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MFN=57066
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DeCS
Descriptor
English
:
Ipilimumab
Descriptor
Spanish
:
ipilimumab
Descriptor
Portuguese
:
Ipilimumab
Synonyms
English
:
Anti CTLA 4 MAb Ipilimumab
Anti-CTLA-4 MAb Ipilimumab
Ipilimumab, Anti-CTLA-4 MAb
MDX 010
MDX CTLA 4
MDX-010
MDX-CTLA-4
MDX010
Yervoy
Tree Number:
D12.776.124.486.485.114.224.060.798
D12.776.124.790.651.114.224.060.798
D12.776.377.715.548.114.224.200.798
Definition
English
:
An anti-CTLA-4
ANTIGEN
monoclonal antibody initially indicated for the treatment of certain types of metastatic
MELANOMA
. Its mode of actions may include blocking of CTLA-4 mediated inhibition of CYTOTOXIC T
LYMPHOCYTES
, allowing for more efficient destruction of target tumor cells.
Pharmacological Action:
Antineoplastic Agents, Immunological
See Related
English
:
CTLA-4 Antigen
History Note
English
:
2018(2012)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57066
Unique Identifier:
D000074324
Occurrence in VHL
:
Similar:
DeCS