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MFN=57080
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DeCS
Descriptor
English
:
Anoctamin-1
Descriptor
Spanish
:
anoctamina-1
Descriptor
Portuguese
:
Anoctamina-1
Synonyms
English
:
Anoctamin 1
TMEM16A Protein
Transmembrane Protein 16A
Tree Number:
D12.776.157.530.400.175.032.500
D12.776.543.550.450.175.032.500
D12.776.543.585.400.175.032.500
Definition
English
:
An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal
muscles
that functions in transepithelial anion transport and smooth
muscle contraction
. It is essential for the function of the
INTERSTITIAL CELLS OF CAJAL
and plays a major role in chloride
conduction
by airway
epithelial cells
and in tracheal
cartilage
development.
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57080
Unique Identifier:
D000075369
Occurrence in VHL
:
Similar:
DeCS