Search on:
MFN=57084
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Sodium-Hydrogen Exchanger 1
Descriptor
Spanish
:
Intercambiador 1 de sodio-hidrógeno
Descriptor
Portuguese
:
Trocador 1 de Sódio-Hidrogênio
Synonyms
English
:
Na(+)-H(+) Exchanger 1
SLC9A1 Protein
Sodium Hydrogen Exchanger 1
Solute Carrier Family 9 Member 1
Tree Number:
D12.776.157.530.450.162.775.500
D12.776.157.530.937.703.500
D12.776.543.550.190.775.500
D12.776.543.585.450.162.775.500
D12.776.543.585.937.828.500
Definition
English
:
A sodium-hydrogen antiporter expressed by many cell types, especially on the basolateral surfaces of
EPITHELIAL CELLS
. It functions through an inward
sodium
ion chemical
gradient
to eliminate acids (
protons
) generated by
metabolism
and regulate intracellular pH. It is highly sensitive to
AMILORIDE.
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57084
Unique Identifier:
D000074082
Occurrence in VHL
:
Similar:
DeCS