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MFN=57116
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DeCS
Descriptor
English
:
Sp7 Transcription Factor
Descriptor
Spanish
:
factor de transcripción Sp7
Descriptor
Portuguese
:
Fator de Transcrição Sp7
Synonyms
English
:
Osterix Protein
Transcription Factor, Sp7
Tree Number:
D12.776.260.522.750.937
D12.776.930.375.750.937
Definition
English
:
An Sp transcription factor that contains three
CYS2-HIS2 ZINC FINGERS
. It binds to GC RICH SEQUENCES and performs an essential function in regulating
gene expression
for differentiation of
OSTEOBLASTS
.
Mutations
in the SP7 gene are associated with type 12
OSTEOGENESIS IMPERFECTA.
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57116
Unique Identifier:
D000076182
Occurrence in VHL
:
Similar:
DeCS