Search on: MFN=57119 
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Descriptor English:   MutS Homolog 3 Protein 
Descriptor Spanish:   proteína 3 homóloga de MutS 
Descriptor Portuguese:   Proteína 3 Homóloga a MutS 
Synonyms English:   Mismatch Repair Protein 1  
Tree Number:   D12.776.260.556.875
Definition English:   A MutS homolog protein and component of post-replicative DNA MISMATCH REPAIR. It forms a heterodimer with MUTS HOMOLOG 2 PROTEIN (MSH2) and recognizes large insertion-deletion loops up to 13 nucleotides in length. This directs downstream events such as strand discrimination, excision, and resynthesis. 
History Note English:   2018 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   57119 
Unique Identifier:   D000074081 

Occurrence in VHL:
 

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