Search on: MFN=57123 
Descriptors Found: 1
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Descriptor English:   Cell Adhesion Molecule-1 
Descriptor Spanish:   molécula 1 de adhesión celular 
Descriptor Portuguese:   Molécula 1 de Adesão Celular 
Synonyms English:   Adhesion Molecule-1, Cell
CADM1 Protein
Cell Adhesion Molecule 1
IGSF4 Protein
Molecule-1, Cell Adhesion
TSLC1 Protein
Tumor Suppressor in Lung Cancer 1 Protein  
Tree Number:   D12.776.395.550.200.115
D12.776.543.550.200.128
D23.050.301.350.115
Definition English:   A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation. 
See Related English:   Immunoglobulin Domains
 
History Note English:   2018 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   57123 
Unique Identifier:   D000075982 

Occurrence in VHL:
 

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DeCS