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DeCS
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Descriptor English:
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NEDD8 Protein
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Descriptor Spanish:
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proteína NEDD8
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Descriptor Portuguese:
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Proteína NEDD8
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Synonyms English:
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NEDD 8 Protein
NEDD-8 Protein
NEDD8, Ubiquitin-like Protein
Neural Precursor Cell Expressed Developmentally Down Regulated Protein 8
Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8
Ubiquitin like Protein NEDD8
Ubiquitin-like Protein NEDD8
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Tree Number:
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D12.776.947.218
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Definition English:
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A ubiquitin-like protein that functions in CELL CYCLE regulation and embryogenesis. It is attached covalently to its substrates following activation by the UBIQUITIN-ACTIVATING ENZYME E1-UBA3 enzyme complex. NEDD8 attaches to CULLINS, activating their E3 UBIQUITIN LIGASE activity, to promote polyubiquitination and degradation of CYCLINS and regulatory proteins |
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History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57143
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Unique Identifier:
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D000075687
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Occurrence in VHL:
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Similar:
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DeCS
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