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MFN=57253
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DeCS
Descriptor
English
:
MYND Domains
Descriptor
Spanish
:
dominios MYND
Descriptor
Portuguese
:
Domínios MYND
Synonyms
English
:
Domain, MYND
Domains, MYND
MYND Domain
MYND Motif
MYND Motifs
Motif, MYND
Motifs, MYND
Zinc Finger MYND Type
Zinc Finger MYND-Type
Tree Number:
G02.111.570.820.709.275.500.985.375
G02.111.570.820.709.275.750.500.474
Definition
English
:
Zinc
finger
domains (named for myeloid, Nervy and DEAF-1) that occur in a variety of eukaryotic
proteins
, including RUNT-RELATED TRANSCRIPTION FACTOR 1 . They are characterized by a cluster of
cysteine
and
histidine
residues with conserved spacing that forms the zinc-binding motif and have beta-beta-alpha (see BETA-SHEET and ALPHA-HELIX) topology,
similar
to LIM domains (see
LIM DOMAIN PROTEINS
) and
RING FINGER DOMAINS
.
MYND domains
function as protein interaction motifs and have affinity for
PROLINE-RICH PROTEIN DOMAINS.
History Note
English
:
2018
Allowable Qualifiers
English
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Record Number:
57253
Unique Identifier:
D000074608
Occurrence in VHL
:
Similar:
DeCS