Search on: MFN=57254 
Descriptors Found: 1
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Descriptor English:   PHD Zinc Fingers 
Descriptor Spanish:   dedos de zinc PHD 
Descriptor Portuguese:   Dedos de Zinco PHD 
Synonyms English:   Domain, PHD
Domain, PHD Finger
Domains, PHD
Domains, PHD Finger
Finger Domain, PHD
Finger Domains, PHD
Finger, PHD
Finger, PHD Zinc
Fingers, PHD
Fingers, PHD Zinc
Motif, PHD
Motifs, PHD
PHD Domain
PHD Domains
PHD Finger
PHD Finger Domain
PHD Finger Domains
PHD Fingers
PHD Motif
PHD Motifs
PHD Zinc Finger
Zinc Finger, PHD
Zinc Fingers, PHD  
Tree Number:   G02.111.570.820.709.275.500.985.438
Definition English:   Zinc finger domains of approximately 50 to 80 amino acids in length that are characterized by a conserved Cysteine(3)-Histidine-Cysteine(4) amino acid motif which coordinates binding of two zinc ions. They are similar structurally to RING FINGER DOMAINS, with a globular fold topology of two BETA-SHEETS and an ALPHA-HELIX. PHD fingers occur in many proteins that function in chromatin-mediated gene expression and EPIGENETICS such as POLYCOMB-GROUP PROTEINS. 
History Note English:   2018 
Allowable Qualifiers English:  
DE drug effects GE genetics
IM immunology PH physiology
RE radiation effects  
Record Number:   57254 
Unique Identifier:   D000075925 

Occurrence in VHL: 		 

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DeCS