Pesquisa sobre: MFN=56983 
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Descritor Inglês:   MTOR Associated Protein, LST8 Homolog 
Descritor Espanhol:   proteína asociada a MTOR, homóloga de LST8 
Descritor Português:   Homólogo LST8 da Proteína Associada a MTOR 
Sinônimos Inglês:   G protein beta Subunit-like Polypeptide
GBetaL Protein
mLST8 Protein
G protein beta Subunit like Polypeptide  
Categoria:   D05.500.337.250
Definição Inglês:   An adaptor protein, consisting of seven WD REPEATS along its length, that functions as a component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 and mTORC2 complex. It interacts directly with MTOR to enhance its kinase activity and stabilizes the MTOR-RPTOR PROTEIN interaction in nutrient-poor conditions, favoring RPTOR inhibition of MTOR activity. 
Nota Histórica Inglês:   2018 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   56983 
Identificador Único:   D000076242 

Ocorrência na BVS:
MEDLINE     22