Pesquisa sobre: MFN=56994 
Descritores Encontrados: 1
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Descritor Inglês:   Katanin 
Descritor Espanhol:   katanina 
Descritor Português:   Katanina 
Categoria:   D08.811.277.040.013.500.250
D08.811.277.040.025.024.250
D12.776.157.025.750.250
D12.776.220.600.450.325
D12.776.631.560.338
Definição Inglês:   An AAA ATPase consisting of the 60 kDa ATPase subunit (p60 subunit A1) which severs MICROTUBULES, and an 80 kDa accessory protein (p80 subunit B1), which targets the enzyme to the CENTROSOME. It releases microtubules from the mitotic SPINDLE POLES to allow depolymerization and poleward motion of chromosomes. It is also a regulator of microtubule dynamics in NEURONAL OUTGROWTH. 
Relacionados Inglês:   AAA Domain
 
Nota Histórica Inglês:   2018 (1993) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   56994 
Identificador Único:   D000074201 

Ocorrência na BVS:
 

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